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Virtanen A, Toimela T, Tihtonen K, Sarkanen JR, Huttala O, Heinonen T, Uotila J. Strong inhibitory effect of pre-eclampsia serum on angiogenesis detection in vitro by human cell-based angiogenesis tests. Pregnancy Hypertension: An international journal of women's cardiovascular health In press, 2016.

Huttala O, Mysore R, Sarkanen JR, Heinonen T, Olkkonen VM, Ylikomi T. Differentiation of human adipose stromal cells in vitro into insulin-sensitive adipocytes. Cell Tissue Res 366(1):63-74, 2016.

Mannerström M, Zou J, Toimela T, Pyykkö I, Heinonen T. The applicability of conventional cytotoxicity assays to predict safety/toxicity of mesoporous silica nanoparticles, silver and gold nanoparticles and multi-walled carbon nanotubes. Toxicology in Vitro 37:113-120, 2016. DOI:10.1016/j.tiv.2016.09.012.

Bondarenko OM, Heinlaan M, Sihtmäe M, Ivask A, Kurvet I, Joonas E, Jemec A, Mannerström M, Heinonen T, Rekulapelly R, Singh S, Zou J, Pyykkö I, Drobne D, Kahru A. Multilaboratory evaluation of 15 bioassays for (eco)toxicity screening and hazard ranking of engineered nanomaterials: FP7 project NANOVALID. Nanotoxicology 10(9):1-45, 2016.

Huttala O, Vuorenpää H, Toimela T, Uotila J, Kuokkanen H, Ylikomi T, Sarkanen JR, Heinonen T. Human vascular model with defined stimulation medium - A characterisation study. Altex 32(2):125-36, 2015.

Vuorenpaa H, Ikonen L, Kujala K, Huttala O, Sarkanen JR, Ylikomi T, Aalto-Setälä K, Heinonen T. Novel in vitro cardiovascular contructs composed of a vascular-like network and cardiomyocytes. In vitro Cellular & Molecular developmental biology- Animal 50(4):275-86, 2014.

Zou J, Feng H, Mannerström M, Heinonen T, Pyykkö I: Toxicity of silver nanoparticle in rat ear and BALB/c 3T3 cell line. Journal of Nanobiotechnology 12:52, 2014.

Tuula Heinonen ja Hanna Tähti: Eläinkokeeton toksikologia kemikaalien turvalllisuustestauksessa. Duodecim 129: 1686-94, 2013.

Heinonen T, Tähti H: Eläinkokeeton toksikologia kemikaalien turvallisuustestauksessa. Duodecim 129: 1686-94, 2013.

Heinonen T, Louekari K, Tähti H: Need for harmonized strategies and improved assessment of carcinogenic and genotoxic potencies of chemical substances. Journal of Translational Toxicology 1, 1-12, 2013.

Heinonen T, Tähti H, Vähäkangas K, Blaauboer B, eds. Towards toxicity assessment without animals. 28th workshop of SSCT and FINCOPA seminar 21-23 September 2011, Tampere, Finland. Toxicol In Vitro, 2013, www.elsevier.com/locate/toxinvit

Sarkanen JR, Vuorenpää H, Huttala O, Mannerström B, Kuokkanen H, Miettinen S, Heinonen T, Ylikomi T.: Adipose stromal cell tubule network model provides a versatile tool for vascular research and tissue engineering. Cells Tissues Organs. 196(5):385-97, 2012.

Sarkanen JR, Ruusuvuori P, Kuokkanen H, Paavonen T, Ylikomi T.: Bioactive acellular implant induces angiogenesis and adipogenesis and sustained soft tissue restoration in vivo. Tissue Eng Part A. 18(23-24):2568-80, 2012.

Sarkanen JR, Kaila V, Mannerström B, Räty S, Kuokkanen H, Miettinen S, Ylikomi T.: Human adipose tissue extract induces angiogenesis and adipogenesis in vitro. Tissue Eng Part A. 18(1-2):17-25, 2012.

Adler, S., Basketter, D., Creton, S., Pelkonen, O., van Benthem, J., Zuang, V., Andersen, K.E., Angers-Loustau, A., Aptula, A., Bal-Price, A., Benfenati, E., Bernauer, U., Bessems, J., Bois, F.Y., Boobis, A., Brandon, E., Bremer, S., Broschard, T., Casati, S., Coecke, S., Corvi, R., Cronin, M., Daston, G., Dekant, W., Felter, S., Grignard, E., Gundert-Remy, U., Heinonen, T., Kimber, I., Kleinjans, J., Komulainen, H., Kreiling, R., Kreysa, J., Leite, S.B., Loizou, G., Maxwell, G., Mazzatorta, P., Munn, S., Pfuhler, S., Phrakonkham, P., Piersma, A., Poth, A., Prieto, P., Repetto, G., Rogiers, V., Schoeters, G., Schwarz, M., Serafimova, R., Tahti, H., Testai, E., van Delft, J., van Loveren, H., Vinken, M., Worth, A., Zaldivar, J.M., 2011. Alternative (non-animal) methods for cosmetics testing: current status and future prospects. Arch. Toxicol. 85, 367-485, 2010

Tähti H, Heinonen T. Vaihtoehtoiset menetelmät kemikaalien turvallisuustestauksessa. Solubiologi No 2, 10-16, 2010.

Diallo H. Veri-aivoesteen mallintaminen in vitro. Solubiologis No 2, 17-21,2010.

Heinonen T, Mannerström M. Eläinkokeille vaihtoehtoisten testimenetelmien kehittäminen, optimointi ja validointi. Solubiologi No 2, 23-25, 2010.

Sarkanen JR, Heinonen T. In vitro-verisuonimallin validointi. Solubiologi No 2, 26-33, 2010.

Sarkanen JR, Mannerström M,Vuorenpää H, Uotila J,Ylikomi T, Heinonen T: Intra-Laboratory Pre-Validation of a Human Cell Based in vitro Angiogenesis Assay for Testing Angiogenesis Modulators. Front Pharmacol. 1: 147, 2010.

Tarkkanen AM, Heinonen T, Jõgi R, Mentula S, van der Rest ME, Donskey CJ, Kemppainen T, Gurbanov K & Nord CE : P1A recombinant beta-lactamase prevents emergence of antimicrobial resistance in gut microflora of healthy subjects during intravenous administration of ampicillin. Antimicrob Agents Chemother. 53(6):2455-2462, 2009.

Hallier-Vanuxeem D, Prieto P, Culot M, Diallo H, Landry C, Tähti H, Cecchelli R: New strategy for alerting central nervous system toxicity: Integration of blood-brain barrier toxicity and permeability in neurotoxicity assessment. Toxicol In Vitro. 23(3):447-453, 2009.

Nevala H, Ylikomi T & Tähti H: Evaluation of the barrier properties of ARPE-19 cell line for in vitro blood-brain barrier model. Hum Exp Toxicol 27(10):741-749, 2008.

Bläuer M, Tammela TL, Ylikomi T. A novel tissue-slice culture model for non-malignant human prostate. Cell Tissue Res. 332(3):489-498, 2008.

Toimela T, Tähti H & Ylikomi T: Comparison of automated pattern analysis machine vision time lapse system with traditional endpoint measurements in analyzing cell growth and cytotoxicity. ATLA 36:313-325, 2008.

Bläuer M, Heinonen PK, Rovio P & Ylikomi T: Effects of tamoxifen and raloxifene on normal human endometrial cells in an organotypic in vitro model. Eur J Pharmacol 592(1-3):13-18, 2008.

Pärssinen J, Kuukasjärvi T, Karhu R & Kallioniemi A: High-level amplification at 17q23 leads to coordinated overexpression of multiple adjacent genes in breast cancer. Br J Cancer. 96(8):1258-1264, 2007

Sarkanen JR, Nykky J, Siikanen J, Selinummi J, Ylikomi T, & Jalonen, TO: Cholesterol supports the retinoic acid-induced synaptic vesicle formation in differentiating human SH-SY5Y neuroblastoma cells. J Neurochem 102(6):1941-1952, 2007.

Alarmo EL, Rauta J, Kauraniemi P, Karhu R, Kuukasjärvi T & Kallioniemi A: Bone morphogenetic protein 7 is widely overexpressed in primary breast cancer. Genes Chromosomes Cancer. 45(4):411-419, 2006.

Mannerström M, Toimela T, Ylikomi T & Tähti H: The combined use of human neural and liver cell lines and mouse hepatocytes improves the predictability of the neurotoxicity of selected drugs. Toxicol Lett 165(2):195-202, 2006.

Rauta J, Alarmo EL, Kauraniemi P, Karhu R, Kuukasjärvi T & Kallioniemi A: The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours. Breast Cancer Res Treat. 95(3):257-263, 2006.

Selinummi J, Sarkanen JR, Niemistö A, Linne ML, Ylikomi T, Yli-Harja O & Jalonen TO: Quantification of vesicles in differentiating human SH-SY5Y neuroblastoma cells by automated image analysis. Neurosci Lett 396(2):102-107, 2006.

Bläuer M, Heinonen PK, Martikainen PM, Tomas E & Ylikomi T: A novel organotypic culture model for normal human endometrium: regulation of epithelial cell proliferation by estradiol and medroxyprogesterone acetate. Hum Reprod 20:864-871, 2005.

Mannerstöm M & Tähti H: Glucose-uptake as a target of neurological drugs in glial and neuronal cell lines. Toxicol Lett, 151, 87-97, 2004.

Toimela T & Tähti H: Mitochondrial viability and apoptosis induced by aluminum, mercury and methylmercury in cell lines of neural origin. Arch Toxicol, 78, 565-574, 2004.

Kakko I, Toimela T & Tähti H: The toxicity of pyrethroid compounds in neural cell cultures studied with total ATP, mitochondrial enzyme activity and microscopic photographing. Environ Toxicol Pharmacol 15, 95-102, 2004.

Kakko I, Toimela T &Tähti H: Oestradiol potentiates the effect of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line. Altern Lab. Anim. ATLA, 32, 383-390, 2004.

Mannerström M & Tähti H: Modulation of glucose uptake in glial and neuronal cell lines by selected neurological drugs. Toxicol Lett. 151(1):87-97, 2004.

Toimela T, Mäenpää H, Mannerström M & Tähti H: Development of an in vitro blood-brain barrier model-cytotoxicity of mercury and aluminum. Toxicol Appl Pharmacol. 195(1):73-82, 2004.

Mäenpää H, Toimela T, Mannerström M, Saransaari P & Tähti H: Toxicity of selected cationic drugs in retinoblastomal cultures and in cocultures of retinoblastomal and retinal pigment epithelial cell lines. Neurochem Res. 29(1):305-11, 2004.

Szabó A, Varga V, Toimela T, Hiitelä K, Tähti H, Oja SS, Süveges I & Salminen L: Laser treatment of cultured retinal pigment epithelial cells-evaluation of the cellular damage in vitro. J Ocul Pharmacol Ther. 20(3):246-255, 2004.